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Open Access Open Badges Case study

Headache after exposure to ‘date-rape’ drugs

Richard Peatfield1* and Carlos M Villalón2

Author Affiliations

1 Princess Margaret Migraine Clinic, Charing Cross Hospital, London, W6 8RF, UK

2 Departamento de Farmacobiología, Cinvestav-Coapa, Deleg. Tlalpan, 14330, México D.F, Mexico

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SpringerPlus 2013, 2:39  doi:10.1186/2193-1801-2-39

Published: 8 February 2013



We report two patients who developed a prolonged featureless headache, they think after a drink was ‘spiked’. We speculate that each was exposed to scopolamine, resulting in enhanced trigeminal release of vasodilator neuropeptides, including Calcitonin Gene-Related Peptide (CGRP), and thus the headache.